EntoZyme

Transforming waste into value with engineered insects

What is the Challenge?

The global demand for sustainable protein sources is escalating as traditional animal agriculture strains environmental resources. Livestock production consumes one-third of global crop output, yet only 12% of these calories reach human consumption, contributing to 16.5% of worldwide greenhouse gas emissions. Pet food alone accounts for up to 30% of the environmental impact of animal agriculture. Simultaneously, aquaculture relies on overfished sources like anchovy-derived fish meal and oil, further depleting marine ecosystems. Compounding these issues, approximately one-third of all food produced is wasted, with nearly 100 million tonnes ending up in landfills annually. This organic waste generates about 75 million tonnes of CO₂-equivalent emissions each year, primarily as methane, a potent greenhouse gas. Addressing these interconnected challenges requires innovative solutions that can efficiently recycle waste into valuable resources.

What is the Solution?

EntoZyme, established in February 2024 as a spin-out from Macquarie University in Sydney, Australia, is pioneering the use of genetically engineered black soldier flies (BSF) to revolutionize waste management and protein production. By applying synthetic biology, EntoZyme enhances BSF capabilities to process a broader range of organic waste streams, converting them into high-quality proteins and oils suitable for pet food, animal feed, and aquaculture. Their engineered BSF exhibit improved amino acid and lipid profiles, and can express functional ingredients that promote the health and well-being of animals consuming these feeds. Additionally, EntoZyme is positioning BSF as a platform for biomanufacturing high-value products, such as industrial enzymes and bioactive compounds, thereby creating a sustainable and scalable solution to global protein shortages and waste accumulation.

This innovative approach not only mitigates the environmental impact of traditional protein production but also addresses the pressing issue of organic waste in landfills. By diverting waste from landfills and reducing reliance on overfished marine resources, EntoZyme contributes to a circular economy where waste is transformed into valuable commodities. Their work exemplifies how biotechnology can be harnessed to solve complex environmental challenges, offering a promising pathway toward sustainable food systems and waste management practices.

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